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Celecoxib is used to relieve pain, fever, swelling and tenderness caused by osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Celecoxib does not prevent the progression of any type of arthritis. It reduces only the symptoms and signs of arthritis. Celecoxib was approved for patients with familial FAP, who have not had their colons removed. Celebrex is also intended for the relief of acute pain and pain in menstrual cramps (primary dysmenorrhea).

Lowest effective dose should be used for each patient. For management of osteoarthritis, the dose usually is 100 mg twice daily or 200 mg as a single dose. For rheumatoid arthritis, the dose usually is 100 or 200 mg twice a day. For acute pain or menstrual cramps, a dose of 400 mg as a single dose on the first day and then another 200 mg if needed, then 200 mg twice daily as needed. For FAP, the recommended dose is 400 mg twice a day.

Celecoxib is a nonsteroidal anti-inflammatory Buy Celebrex 200 mg 100 mg onlines (NSAIDs), which is used to treat arthritis, pain, menstrual cramps, and colonic polyps. Prostaglandins are chemicals that are important contributors to the inflammation of arthritis that causes pain, fever, swelling and tenderness. Celecoxib blocks the enzyme that makes prostaglandins (cyclooxygenase 2), which leads to lower concentrations of prostaglandins. As a consequence, inflammation and its accompanying pain, fever, swelling and tenderness are reduced. Celecoxib differs from other NSAIDs, it causes less inflammation and ulceration of the stomach and intestine (at least with short-term treatment) and does not interfere with blood clotting. NSAIDs have been found to prevent formation and reduce the size of polyps in patients with a genetic disease, familial adenomatous polyposis (FAP). In FAP, patients develop a large number of polyps in the colon, and polyps invariably become malignant. The only cure for FAP requires removal of the entire colon. Celecoxib is approved as an additional (secondary) treatment in patients with FAP. Cramping and pain during menstruation is associated with prostaglandins, and blocking the production of prostaglandins with celecoxib reduces the cramps and pain.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take only the next regularly scheduled dose as directed. Do not take a double dose of this medication unless your doctor directs otherwise.

Capsules should be stored at a temperature of 25 degrees C (77 degrees Fahrenheit). It's good for brief periods in temperatures between 15-30 degrees (59-86 degrees Fahrenheit).

There are no restrictions on food, beverages, or activities taking celecoxib unless otherwise directed by your doctor. Concomitant use of celecoxib with aspirin or other NSAIDs (eg, ibuprofen, naproxen, etc.) may increase the occurrence of gastro-intestinal ulcers. Fluconazole (Diflucan) increases the concentration of celecoxib in the body, suppressing the collapse of celecoxib in the liver. Thus, treatment with celecoxib should be initiated at the lowest recommended doses in patients treated with fluconazole. Celecoxib increases the concentration of lithium (Eskalith) in the blood by 17%. Thus, lithium therapy should be closely monitored during and after therapy with celecoxib. Persons taking anticoagulant (blood thinner) warfarin (Coumadin), should have their blood tested when initiating or changing celecoxib treatment, particularly in the first few days, any change in the anticoagulant effect. Persons who drink more than 3 alcoholic beverages a day may be at increased risk of developing stomach ulcers when taking NSAIDs, and this may also be true with celecoxib. Celecoxib has not been studied in pregnant women. In animal studies, doses that were twice the maximally recommended dose were harmful to the fetus. Celecoxib should only be used in pregnant women when benefits outweigh the potential risk to the fetus. The use of celecoxib in nursing mothers has not been evaluated.